Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607314 | 1.00 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7609481 | 0.94 | NPC1 (0.59) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL14365418 | 0.94 | NPC1 (0.59) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7887297 | 0.94 | NPC1 (0.64) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7887300 | 0.94 | NPC1 (0.64) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL8345323 | 0.93 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL29881441 | 0.93 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL11134813 | 0.93 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL28820768 | 0.88 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL29882542 | 0.88 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265876-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001064658-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |
| US-6177574-B1 | REACTING 4,4'-BIS(BENZOXAZOL-2-YL)STILBENE WITH AN AMINOPHENOL AT A TEMPERATURE OF AT LEAST 200 DEGREES C IN THE PRESENCE OF AN INERT ORGANIC SOLVENT | EASTMAN CHEMICAL COMPANY | 2001-01-23 | — | — | US | disclosed |