Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | GFER | P55789 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365418 | 1.00 | NPC1 (0.59) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL29881441 | 0.96 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL11134813 | 0.96 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL8345323 | 0.96 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7887300 | 0.95 | NPC1 (0.64) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7887297 | 0.95 | NPC1 (0.64) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7607309 | 0.94 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL7607314 | 0.94 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL28820768 | 0.89 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 | |
| SCHEMBL29882542 | 0.89 | NPC1 (0.57) | NPC1RAB9AGFERHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7306809-B2 | Optically activated particles for use in cosmetic compositions | LIPO CHEMICALS, INC. (US) | 2007-12-11 | — | — | US | disclosed |
| US-7306809-B2 | Optically activated particles for use in cosmetic compositions | LIPO CHEMICALS, INC. (US) | 2007-12-11 | — | — | US | disclosed |
| CN-1167690-C | Preparation of mixtures of benzoxazole-stilbene compounds | 伊斯曼化学公司 | 2004-09-22 | — | — | CN | disclosed |
| CN-1407976-A | Preparation of mixtures of benzoxazolyl-stilbene compounds | EASTMAN CHEM CO (US) | 2003-04-02 | — | — | CN | disclosed |
| EP-1265876-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001064658-A1 | PREPARATION OF MIXTURES OF BENZOXAZOLYL-STILBENE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |