SCHEMBL760739

SCHEMBL760739

C[C@H]1CN(c2ccc(C(F)(F)F)cn2)CC[C@@H]1Oc1cc(-c2cc(F)cc(F)c2)nn1CC1OCCO1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HRH3 Q9Y5N1 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ABL1 P00519 1/20 0.36
LMNA P02545 1/20 0.36
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
SCD O00767 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
GPR119 Q8TDV5 1/20 0.36
SLC6A9 P48067 4/20 0.36
TRPA1 O75762 1/20 0.35
TMEM97 Q5BJF2 1/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL760740 1.00 CHRM2 (0.37) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL760741 1.00 CHRM2 (0.37) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL15745707 0.87 HRH3 (0.40) CHRM2CHRM5CHRM1CHRM3HRH3
SCHEMBL761309 0.86 CHRM2 (0.37) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL761310 0.86 CHRM2 (0.37) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL15745705 0.86 HRH3 (0.37) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL761308 0.86 CHRM2 (0.37) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL10212982 0.81 CNR2 (0.34) L3MBTL1HRH3KDM4EABL1LMNA
SCHEMBL15745706 0.80 SCD (0.39) CHRM2CHRM5CHRM1CHRM3L3MBTL1
SCHEMBL12371195 0.80 DPP4 (0.33) L3MBTL1KDM4EABL1LMNADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2050745-B1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA AGRITECHNO CO LTD (JP) 2012-03-21 EP disclosed
US-7994094-B2 N-pyridylpiperidine compound, method for producing the same, and pest control agent OTSUKA AGRITECHNO CO., LTD. (JP) 2011-08-09 US disclosed
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
EP-2050745-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Otsuka Chemical Co., Ltd. (JP) 2009-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT HRH4, NOX4, PRDX4 CHRM2 48/4885CHRM5 31/4885CHRM1 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.