SCHEMBL7607424

SCHEMBL7607424

CCCCCCCCc1ccc2c(c1)c(F)c(F)c1cc(Br)ccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.42
PPARA Q07869 1/20 0.42
RORA P35398 1/20 0.41
RORC P51449 1/20 0.41
RORB Q92753 1/20 0.41
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
SHBG P04278 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSPD1 P10809 1/20 0.41
ADRB3 P13945 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610928 1.00 KAT8 (0.42) KAT8PPARARORARORCRORB
SCHEMBL7606851 0.94 NPC1 (0.46) KAT8HTR1ANPC1GAANFKB1
SCHEMBL7607203 0.91 KAT8 (0.49) KAT8PPARARORARORCRORB
SCHEMBL7611678 0.91 KAT8 (0.49) KAT8PPARARORARORCRORB
SCHEMBL19621925 0.90 KAT8 (0.38) KAT8PPARARORARORCRORB
SCHEMBL7523369 0.81 EIF4A1 (0.41) RORARORCRORBESR1ADRA2A
SCHEMBL5415840 0.79 HSD17B10 (0.45) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL27559379 0.78 ESR1 (0.43) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL17878901 0.77 SRC (0.40) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1893401 0.77 SRC (0.40) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed
EP-0837851-B1 FLUORINATED PHENANTHRENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2002-05-29 EP disclosed
US-5888422-A Fluorinated phenanthrene derivatives and their use in liquid-crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1999-03-30 US disclosed
EP-0837851-A1 FLUORINATED PHENANTHRENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-29 EP disclosed
WO-1997002247-A1 FLUORINATED PHENANTHRENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-23 WO disclosed