Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610928 | 0.90 | KAT8 (0.42) | KAT8PPARARORARORCRORB | |
| SCHEMBL7607424 | 0.90 | KAT8 (0.42) | KAT8PPARARORARORCRORB | |
| SCHEMBL7606851 | 0.84 | NPC1 (0.46) | KAT8HTR1ANPC1GAANFKB1 | |
| SCHEMBL7611678 | 0.81 | KAT8 (0.49) | KAT8PPARARORARORCRORB | |
| SCHEMBL7607203 | 0.81 | KAT8 (0.49) | KAT8PPARARORARORCRORB | |
| SCHEMBL27955065 | 0.81 | PTGS2 (0.48) | KAT8PPARARORARORCRORB | |
| SCHEMBL17878901 | 0.78 | SRC (0.40) | ESR1ESR2ADRA2AADORA3TACR2 | |
| SCHEMBL1893401 | 0.78 | SRC (0.40) | ESR1ESR2ADRA2AADORA3TACR2 | |
| SCHEMBL7523369 | 0.75 | EIF4A1 (0.41) | RORARORCRORBESR1HTR1A | |
| SCHEMBL19767756 | 0.75 | SRC (0.38) | ESR1ESR2ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669263-B1 | COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2017-11-22 | — | — | EP | disclosed |