Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31393357 | 0.86 | KMT2A (0.57) | ALDH1A1HNF4AIKBKBKMT2AMEN1 | |
| SCHEMBL6852649 | 0.85 | HNF4A (0.50) | ALDH1A1HSD17B10HNF4ALMNABCAT2 | |
| SCHEMBL28423399 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HNF4ALMNABCAT2 | |
| SCHEMBL28965508 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HNF4ALMNABCAT2 | |
| SCHEMBL31014273 | 0.81 | KMT2A (0.46) | ALDH1A1HNF4ALMNAIKBKBPTGS2 | |
| SCHEMBL17687654 | 0.80 | PDE4A (0.44) | ALDH1A1HSD17B10HNF4ALMNABCAT2 | |
| SCHEMBL4671318 | 0.80 | PDE4A (0.44) | ALDH1A1HSD17B10LMNABCAT2IKBKB | |
| SCHEMBL8747589 | 0.79 | CA12 (0.48) | ALDH1A1HSD17B10HNF4ALMNAFOLH1 | |
| SCHEMBL21486 | 0.79 | HNF4A (0.52) | ALDH1A1HNF4ALMNABCAT2FOLH1 | |
| SCHEMBL1535068 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HNF4ABCAT2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | UNIVERSITY OF PITTSBURGH (US) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | LANCL1, FNTB, DHCR7 | ALDH1A1 1121/4885HSD17B10 37/4885HNF4A 3471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.