SCHEMBL7607930

SCHEMBL7607930

O=S(=O)(Cl)c1ccc(-c2ccc(Sc3ccc(-c4ccc(S(=O)(=O)Cl)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 6/20 0.41
CA2 P00918 6/20 0.41
CA9 Q16790 6/20 0.41
STS P08842 1/20 0.38
PTGS2 P35354 2/20 0.37
MMP3 P08254 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
LMNA P02545 2/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA1 P00915 3/20 0.35
CA14 Q9ULX7 1/20 0.35
ANXA2 P07355 1/20 0.35
S100A10 P60903 1/20 0.35
CTRC Q99895 1/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779793 0.93 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1CA2STS
SCHEMBL150162 0.85 ALDH1A1 (0.60) ALDH1A1HSD17B10TDP1CA12CA2
SCHEMBL5891023 0.85 ALDH1A1 (0.60) ALDH1A1HSD17B10TDP1CA12CA2
SCHEMBL6503207 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10TDP1CA12CA2
Water SCHEMBL7024182 0.83 ALDH1A1 (0.57) ALDH1A1HSD17B10TDP1CA12CA2
Hydrochloric Acid SCHEMBL7353403 0.81 DDAH1 (0.56) ALDH1A1HSD17B10TDP1CA2STS
SCHEMBL2331077 0.79 MAPT (0.52) ALDH1A1HSD17B10TDP1CA12CA2
SCHEMBL2263715 0.78 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1CA12CA2
SCHEMBL651902 0.77 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1CA12CA2
SCHEMBL21993320 0.76 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770599-B1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS (JP) 2002-08-07 EP disclosed
US-5811571-A HALOGENATING AN AROMATIC OR HETEROAROMATIC METHYL SULFIDE OR METHYL SULFOXIDE IN PRESENCE OF WATER SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-09-22 US disclosed
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP disclosed