Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842063 | 0.89 | PLA2G4B (0.35) | PLA2G4BUSP2HTTLPAR5ABCB1 | |
| SCHEMBL1906579 | 0.89 | PLA2G4B (0.35) | PLA2G4BUSP2HTTLPAR5ABCB1 | |
| SCHEMBL1905764 | 0.89 | PLA2G4B (0.35) | PLA2G4BUSP2HTTLPAR5ABCB1 | |
| SCHEMBL8094936 | 0.88 | MCHR1 (0.41) | MCHR1CNR1CNR2PTPN11KMT2A | |
| SCHEMBL5558959 | 0.88 | PLA2G4B (0.38) | PLA2G4BUSP2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL3922564 | 0.84 | KDM4E (0.35) | PLA2G4BHTTABCB1KDM4ESMN1; SMN2 | |
| SCHEMBL580178 | 0.83 | MEN1 (0.39) | KDM4ESMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL7254047 | 0.81 | PLA2G4B (0.44) | PLA2G4BUSP2HTTLPAR5CNR2 | |
| SCHEMBL8855632 | 0.80 | MAPT (0.36) | PLA2G4BUSP2HTTKDM4ESMN1; SMN2 | |
| SCHEMBL6397184 | 0.79 | ABCB1 (0.39) | ABCB1KDM4EKMT2ADHPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006452-A1 | Plastic lens systems, compositions, and methods | OPTICAL DYNAMICS CORP. | 2002-01-17 | — | — | US | disclosed |