SCHEMBL580178

SCHEMBL580178

CCCOCC(O)COc1cccc(-c2nc(-c3ccc(OC)cc3)nc(-c3cccc(OCC(O)COCCC)c3O)n2)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
CASR P41180 6/20 0.38
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
CYP1A2 P05177 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
GAA P10253 2/20 0.36
HIF1A Q16665 2/20 0.36
LMNA P02545 2/20 0.36
AGTR1 P30556 1/20 0.36
CYP2D6 P10635 1/20 0.36
GBA1 P04062 1/20 0.36
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580177 0.86 NR2E1 (0.48) MEN1KMT2ANPC1CASRMAPT
SCHEMBL5558959 0.86 PLA2G4B (0.38) MEN1KMT2AMAPTSMN1; SMN2CYP1A2
SCHEMBL7607965 0.83 PLA2G4B (0.36) KMT2AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL277377 0.82 MAPT (0.43) MEN1KMT2ANPC1CASRMAPT
SCHEMBL4656279 0.82 KMT2A (0.40) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL4554162 0.80 TDP1 (0.41) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL7887570 0.80 MAPT (0.43) NPC1MAPTSMN1; SMN2POLBCYP1A2
SCHEMBL30996060 0.80 NR2E1 (0.46) MEN1KMT2ANPC1CASRMAPT
SCHEMBL5163603 0.79 KMT2A (0.40) MEN1KMT2ANPC1MAPTSMN1; SMN2
SCHEMBL15127483 0.78 CASR (0.42) MEN1KMT2ANPC1CASRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007110415-A2 USE OF DIACETYL TRIMERS AND COSMETIC OR THERAPEUTIC FORMULATIONS CONTAINING THESE COMPOUNDS SYMRISE GMBH & CO. KG (DE) 2007-10-04 WO claimed
US-20240237643-A1 COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY SYMRISE AG (DE) 2024-07-18 US disclosed
US-20240216248-A1 MICROBIAL GLYCOLIPIDS ANALYTICON DISCOVERY GMBH (DE) 2024-07-04 US disclosed
US-12023396-B2 Flavour and fragrance compositions comprising acetophenone derivatives SYMRISE AG (DE) 2024-07-02 US disclosed
US-12016944-B2 Mixtures comprising a protein extract for the treatment of human skin and/or hair SYMRISE AG (DE) 2024-06-25 US disclosed
CN-118141701-A Composition containing benzoic acid derivative or furoic acid derivative and use of the derivative for emulsion and foam stability 西姆莱斯股份公司 2024-06-07 CN disclosed
EP-4373462-A1 COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL Symrise AG (DE) 2024-05-29 EP disclosed
US-20240122816-A1 ARTICLES FOR INDIRECT TRANSFER OF COSMETIC ACTIVES TO SKIN SYMRISE AG (DE) 2024-04-18 US disclosed
US-20240122834-A1 MEDICAMENT FOR PREVENTION AND TREATMENT OF HYPERPIGMENTATION SYMRISE AG (DE) 2024-04-18 US disclosed
US-11938208-B2 Antimicrobial mixture SYMRISE AG (DE) 2024-03-26 US disclosed
US-20050249688-A1 Hair care composition KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-10 US disclosed
EP-1326955-B1 MULTI-PHASE SOAP SYMRISE GMBH & CO KG (DE) 2004-12-22 EP disclosed
EP-1341752-B1 NOVEL INDANYLIDENE COMPOUNDS SYMRISE GMBH & CO KG (DE) 2004-08-04 EP disclosed
US-6673756-B2 MULTILAYER; CUTTING, JOINING UNDER PRESSURE SYMRISE GMBH & CO. KG (DE) 2004-01-06 US disclosed
WO-2003092643-A1 LIGHT-PROTECTION FORMULATIONS USING ACRYLONITRILE DERIVATIVES SYMRISE GMBH & CO. KG (DE) 2003-11-13 WO disclosed
WO-2003084496-A1 LIGHT-PROTECTIVE PREPARATIONS CONTAINING A PHOTOSTABLE UV-A FILTER SYMRISE GMBH & CO. KG (DE) 2003-10-16 WO disclosed
EP-1326955-A1 MULTI-PHASE SOAP HAARMANN & REIMER GMBH (DE) 2003-07-16 EP disclosed
US-20020173436-A1 Multilayer; cutting, joining under pressure SYMRISE GMBH & CO. KG (DE) 2002-11-21 US disclosed
US-20020143203-A1 Novel indanylidene compounds SYMRISE GMBH & CO. KG (DE) 2002-10-03 US disclosed
WO-2002024857-A1 MULTI-PHASE SOAP HAARMANN & REIMER GMBH (DE) 2002-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023396-B2 Flavour and fragrance compositions comprising acetophenone derivatives FAAH2, ADH5, NISCH MEN1 3838/4885KMT2A 3181/4885NPC1 1744/4885
US-20240122834-A1 MEDICAMENT FOR PREVENTION AND TREATMENT OF HYPERPIGMENTATION MC1R, OR51E2, TYR MEN1 3943/4885KMT2A 4263/4885NPC1 1473/4885
US-20050249688-A1 Hair care composition KRT18, CUTA, LAGE3 MEN1 1970/4885KMT2A 584/4885NPC1 4465/4885
US-20020143203-A1 Novel indanylidene compounds CUTA, NISCH, ERCC4 MEN1 2511/4885KMT2A 3196/4885NPC1 1907/4885
US-20240216248-A1 MICROBIAL GLYCOLIPIDS UGCG, SGMS1, GPR119 MEN1 2789/4885KMT2A 2648/4885NPC1 1000/4885
US-20240122816-A1 ARTICLES FOR INDIRECT TRANSFER OF COSMETIC ACTIVES TO SKIN CUTA, POLR1C, SLC16A7 MEN1 2879/4885KMT2A 679/4885NPC1 1614/4885
US-11938208-B2 Antimicrobial mixture GNPAT, GMDS, DDOST MEN1 4312/4885KMT2A 4755/4885NPC1 1559/4885
US-20240237643-A1 COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY ZC3HAV1, SAMHD1, ZC3HAV1L MEN1 4207/4885KMT2A 3922/4885NPC1 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.