Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054722 | 0.90 | PTPN11 (0.46) | MCHR1PTPN11PDE5APDE4APDE4B | |
| SCHEMBL7249597 | 0.90 | MCHR1 (0.49) | MCHR1PTPN11PDE5APDE4APDE4B | |
| SCHEMBL7607965 | 0.88 | PLA2G4B (0.36) | MCHR1PTPN11LMNAMAPTKMT2A | |
| SCHEMBL1424639 | 0.86 | MCHR1 (0.40) | MCHR1PTPN11PDE5APDE4APDE4B | |
| SCHEMBL5602712 | 0.86 | MCHR1 (0.40) | MCHR1PTPN11PDE5APDE4APDE4B | |
| SCHEMBL31258167 | 0.86 | MCHR1 (0.40) | MCHR1PTPN11PDE5APDE4APDE4B | |
| SCHEMBL4791409 | 0.86 | MCHR1 (0.40) | MCHR1PTPN11PDE5APDE4APDE4B | |
| SCHEMBL16781412 | 0.85 | GRM2 (0.41) | PTPN11 | |
| SCHEMBL8848507 | 0.78 | LTB4R (0.45) | MEN1MAPTKMT2ACNR1CNR2 | |
| SCHEMBL14085534 | 0.77 | MAPT (0.45) | MEN1LMNAMAPTKMT2ADHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087062-A | COINITIATOR INCLUDING ELECTRON ACCEPTOR COMPOUND; EFFICIENCY, PHOTOSENSITIVITY | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0548015-A1 | Tetramethylpiperidine compounds for use as stabilisers for organic materials | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |