Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162293 | 0.92 | LMNA (0.47) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL5033195 | 0.90 | LMNA (0.45) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL10318442 | 0.89 | LMNA (0.44) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL1048643 | 0.87 | LMNA (0.44) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9191001 | 0.85 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL9171058 | 0.85 | LMNA (0.53) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9009061 | 0.83 | LMNA (0.64) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9194255 | 0.83 | LMNA (0.42) | LMNACYP2C19HIF1A | |
| SCHEMBL9194278 | 0.83 | LMNA (0.42) | LMNACYP2C19HIF1A | |
| SCHEMBL2763433 | 0.82 | LMNA (0.38) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886634-B1 | PROCESS FOR PRODUCING IOVERSOL | MALLINCKRODT INC (US) | 2002-04-24 | — | — | EP | claimed |