Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102251 | 0.93 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ANR4A2GRM6 | |
| SCHEMBL5159521 | 0.92 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1KMT2ANR4A2GRM6 | |
| SCHEMBL8978512 | 0.91 | ATM (0.41) | SMN1; SMN2MEN1KMT2ANR4A2GRM6 | |
| SCHEMBL10102254 | 0.88 | ATM (0.39) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL5644282 | 0.88 | ALDH1A1 (0.39) | SMN1; SMN2MEN1KMT2ANR4A2LMNA | |
| SCHEMBL6931279 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL7001887 | 0.87 | EGFR (0.41) | SMN1; SMN2MEN1KMT2ANR4A2GRM6 | |
| SCHEMBL5649363 | 0.87 | NCEH1 (0.37) | SMN1; SMN2MEN1KMT2ANR4A2TSHR | |
| SCHEMBL5646946 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ANR4A2TSHR | |
| SCHEMBL17929226 | 0.86 | ATM (0.38) | SMN1; SMN2MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112264-B1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-11-27 | — | — | EP | disclosed |