Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608140 | 1.00 | CCR5 (0.58) | CCR5KCNH2DRD3 | |
| SCHEMBL7608985 | 0.91 | CCR5 (0.62) | CCR5KCNH2 | |
| SCHEMBL7608991 | 0.91 | CCR5 (0.62) | CCR5KCNH2 | |
| SCHEMBL6104754 | 0.83 | ARG1 (0.48) | CCR5KCNH2DRD3 | |
| SCHEMBL6104756 | 0.83 | ARG1 (0.48) | CCR5KCNH2DRD3 | |
| SCHEMBL5451783 | 0.77 | CCR5 (0.54) | CCR5KCNH2 | |
| SCHEMBL6106521 | 0.74 | ARG1 (0.51) | CCR5KCNH2 | |
| SCHEMBL6106524 | 0.74 | ARG1 (0.51) | CCR5KCNH2 | |
| SCHEMBL5456416 | 0.74 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL7544484 | 0.73 | CCR5 (1.00) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | HALE JEFFREY J (US) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | CCR5, CCR1, CXCR1 | CCR5 1/4885KCNH2 3940/4885DRD3 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.