Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612302 | 0.90 | ALOX5 (0.45) | ALOX5BCHEEPORPTGS1PTGS2 | |
| SCHEMBL7612363 | 0.89 | NPC1 (0.48) | EPORL3MBTL1LMNALTA4H | |
| SCHEMBL7606266 | 0.84 | ELANE (0.42) | ALOX5BCHEPTGS1PTGS2ABCB1 | |
| SCHEMBL7039498 | 0.83 | NPY5R (0.46) | ALOX5PTGS1PTGS2ABCB1ACACB | |
| SCHEMBL7605332 | 0.82 | ABCB1 (0.37) | ALOX5ABCB1 | |
| SCHEMBL7606841 | 0.82 | NR1H3 (0.41) | ABCB1 | |
| SCHEMBL7608227 | 0.81 | PTGS1 (0.40) | ALOX5BCHEEPORPTGS1PTGS2 | |
| SCHEMBL7607642 | 0.80 | NPC1 (0.47) | ALOX5EPORLMNALTA4H | |
| SCHEMBL7609951 | 0.79 | SMN1; SMN2 (0.36) | ALOX5BCHEL3MBTL1LMNA | |
| SCHEMBL7042816 | 0.78 | ABCB1 (0.44) | ALOX5BCHEABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |