SCHEMBL7608372

SCHEMBL7608372

Cc1cc2oc1cc2C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
CA2 P00918 2/20 0.36
POLB P06746 2/20 0.36
TYR P14679 1/20 0.36
ALOX15 P16050 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ATP2A2 P16615 1/20 0.35
ATP2A3 Q93084 1/20 0.35
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20798945 0.89 ALDH1A1 (0.41) CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL157486 0.81
SCHEMBL26193854 0.66 MAOA (0.51) CYP1A2CYP2C19ALDH1A1SMN1; SMN2MAPT
SCHEMBL18052704 0.66 MAOA (0.51) CYP1A2CYP2C19ALDH1A1SMN1; SMN2MAPT
SCHEMBL21500716 0.66 CYP2C9 (0.46) CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL14506378 0.65 ALDH1A1 (0.36) CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL22857635 0.64 HPGD (0.36) CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2
Water SCHEMBL28480832 0.64 CYP2C9 (0.44) CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL27489165 0.64 CYP2C9 (0.44) CYP1A2CYP2C9CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL18595811 0.63 ALDH1A1 (0.33) CYP1A2CYP2C9ALDH1A1SMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240279402-A1 COMPOSITIONS CONTAINING POLYORGANOSILOXANES HAVING POLYPHENYLENE ETHER GROUPS WACKER CHEMIE AG (DE) 2024-08-22 US disclosed
EP-4352130-A1 COMPOSITIONS CONTAINING POLYORGANOSILOXANES HAVING POLYPHENYLENE ETHER GROUPS Wacker Chemie AG (DE) 2024-04-17 EP disclosed
CN-117794982-A Composition containing polyorganosiloxane having polyphenylene ether group 瓦克化学股份公司 2024-03-29 CN disclosed
WO-2022258140-A1 COMPOSITIONS CONTAINING POLYORGANOSILOXANES HAVING POLYPHENYLENE ETHER GROUPS WACKER CHEMIE AG (DE) 2022-12-15 WO disclosed
CN-109627756-B Water heater liner material and preparation method thereof 江门市德众泰工程塑胶科技有限公司 2021-09-03 CN disclosed
US-6469077-B1 HAVING SUPERIOR HEAT RESISTANCE AND FLAME RESISTANCE, AND WHEREIN THE FLAME RESISTANCE IS REMARKABLE WHEN THE RESIN COMPOSITION IS FORMED INTO A THIN MOLDED PRODUCT SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2002-10-22 US disclosed
US-6414091-B2 BLEND OF POLYPHENYLENE ETHER AND POLYSILOXANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-02 US disclosed
US-20020012782-A1 Blend containing phosphoric ester; dielectric sheets SUMITOMO CHEMICAL COMPANY, LIMITED 2002-01-31 US disclosed
US-6322882-B1 CONTAINING A PHOSPHORIC ESTER AND A DISPERSED SUBSTANCE CONTAINING A POLYSILOXANE AND SILICA HAVING AN ASPECT RATIO OF NOT LESS THAN ABOUT 2; SUPERIOR HEAT RESISTANCE AND FLAME RESISTANCE WITHOUT USE OF ANY HALOGEN-CONTAINING MATERIALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-27 US disclosed
US-20010014723-A1 Thermoplastic resin, process for producing same and theroplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-16 US disclosed
US-5336713-A Polyphenylene ether and a polyarylene sulfide; excellent welding property SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-09 US disclosed
US-5296533-A Mixture of polyphenylene ether, polyamide, polystyrene with inorganic powder SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-22 US disclosed
EP-0570972-A1 Polyphenylene ether polyarylene sulfide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-24 EP disclosed
EP-0568039-A1 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-03 EP disclosed
US-5218048-A Blend of thermoplastic resin, functional monomer and diamino compound; impact strength, stiffness SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-08 US disclosed
EP-0542536-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-19 EP disclosed
EP-0542296-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-19 EP disclosed
US-5189103-A Blend with polyolefin; impact strength, solvent resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-23 US disclosed
EP-0440923-A1 Polyolefin resinsompositions and process for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-14 EP disclosed
EP-0440922-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-14 EP disclosed