SCHEMBL760842

SCHEMBL760842

C[Si](C)(C)c1ccc(N(c2ccccc2)c2ccc3c(-c4ccc(-c5ccc(-c6ccccc6)s5)cc4)c4cc(N(c5ccccc5)c5ccc([Si](C)(C)C)cc5)ccc4c(-c4ccc(-c5ccc(-c6ccccc6)s5)cc4)c3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.43
MAPT P10636 1/20 0.36
HSD17B1 P14061 3/20 0.33
HSD17B2 P37059 3/20 0.33
ABCB1 P08183 1/20 0.32
NQO2 P16083 3/20 0.31
CYP2E1 P05181 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2B6 P20813 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
NFKB1 P19838 1/20 0.30
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12700834 0.92 APP (0.41) APPMAPTHSD17B1HSD17B2ABCB1
SCHEMBL12700907 0.90 APP (0.39) APPMAPTHSD17B1HSD17B2NQO2
SCHEMBL12700849 0.90 APP (0.39) APPMAPTHSD17B1HSD17B2NQO2
SCHEMBL12700904 0.90 APP (0.39) APPMAPTHSD17B1HSD17B2NQO2
SCHEMBL760840 0.90 TDP1 (0.33) MAPTCYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL14516043 0.88 ACHE (0.33) MAPTCYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL760861 0.88 ACHE (0.33) MAPTCYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL14516040 0.88 ACHE (0.33) MAPTCYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL14515982 0.88 TDP1 (0.33) MAPTCYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL12700832 0.87 APP (0.37) APPMAPTHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8137823-B2 Anthracene derivatives, process for preparation thereof, and organic electronic light emitting device using the same LG CHEM, LTD. (KR) 2012-03-20 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT APP 85/4885MAPT 1491/4885HSD17B1 1898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.