Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 15/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 14/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415008 | 0.76 | GRIA2 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9860476 | 0.74 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL6563992 | 0.73 | HSD17B1 (0.60) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL30186296 | 0.72 | HSD17B1 (0.65) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL30963923 | 0.72 | HSD17B1 (0.65) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3641638 | 0.71 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL10899166 | 0.70 | PTGS1 (0.50) | — | |
| SCHEMBL26681320 | 0.70 | HSD17B1 (0.56) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1180152 | 0.70 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL26682030 | 0.69 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |