Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731517 | 0.92 | L3MBTL1 (0.39) | L3MBTL1TDP1MEN1KMT2ATSHR | |
| SCHEMBL9804353 | 0.87 | TDP1 (0.36) | P2RX3S1PR1S1PR3L3MBTL1TDP1 | |
| SCHEMBL10414342 | 0.87 | L3MBTL1 (0.39) | P2RX3S1PR1S1PR3L3MBTL1TDP1 | |
| SCHEMBL9804293 | 0.87 | TDP1 (0.36) | P2RX3S1PR1S1PR3L3MBTL1TDP1 | |
| SCHEMBL7612806 | 0.87 | TSHR (0.36) | S1PR1S1PR3L3MBTL1TDP1MEN1 | |
| SCHEMBL9804281 | 0.85 | S1PR1 (0.36) | S1PR1S1PR3L3MBTL1TDP1MEN1 | |
| SCHEMBL10569790 | 0.85 | S1PR1 (0.38) | P2RX3S1PR1S1PR3TDP1MEN1 | |
| SCHEMBL10564119 | 0.85 | L3MBTL1 (0.38) | S1PR1S1PR3L3MBTL1TDP1MEN1 | |
| SCHEMBL10414341 | 0.85 | S1PR1 (0.38) | P2RX3S1PR1S1PR3TDP1MEN1 | |
| SCHEMBL10414405 | 0.84 | TSHR (0.37) | S1PR1S1PR3FPR2SCN9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333131-B1 | Plant protective agent based on pyrazolecarboxylic acid derivatives | HOECHST AG (DE) | 1993-10-27 | — | — | EP | claimed |
| EP-0333131-A1 | Plant protective agent based on pyrazolecarboxylic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-20 | — | — | EP | claimed |
| EP-0850565-B1 | Synergistic herbicidal agents | BAYER CROPSCIENCE GMBH (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6159900-A | Synergistic herbicidal agents | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| US-5945541-A | Plant protection agents based on pyrazolecarboxylic acid derivatives | HOECHST SCHERING AGREVO GMBH (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0850565-A1 | Synergistic herbicidal agents | Hoechst Schering AgrEvo GmbH (DE) | 1998-07-01 | — | — | EP | disclosed |
| EP-0635996-B1 | PYRAZOLINES FOR THE PROTECTION OF CROP PLANTS AGAINST HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-02-11 | — | — | EP | disclosed |
| US-5703008-A | Pyrazolines for protecting crop plants against herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| US-5700758-A | APPLYING TO SAFEN PLANTS AGAINST PHOTOTOXICITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | disclosed |
| EP-0543878-B1 | PLANT PROTECTING AGENTS CONTAINING ISOXAZOLINE OR ISOTHIAZOLINE AND NEW ISOXAZOLINES AND ISOTHIAZOLINES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-08 | — | — | EP | disclosed |
| US-5521143-A | USED WITH HERBICIDES, CEREAL CROPS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |
| WO-1992003053-A1 | PLANT PROTECTING AGENTS CONTAINING ISOXAZOLINE OR ISOTHIAZOLINE AND NEW ISOXAZOLINES AND ISOTHIAZOLINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-05 | — | — | WO | disclosed |
| WO-1991018907-A1 | PLANT-PROTECTING SUBSTITUTED ISOXAZOLINES, ISOXAZOLES, ISOTHIAZOLINES AND ISOTHIAZOLES, PROCESS FOR PRODUCING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-12 | — | — | WO | disclosed |
| US-5037468-A | Prevent phytotoxic damage by herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |
| WO-1991008202-A1 | ISOXAZOLINES, METHOD OF PREPARATION THEREOF, AND THEIR USE AS PLANT-PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-13 | — | — | WO | disclosed |
| WO-1991007874-A1 | PYRAZOLINES FOR THE PROTECTION OF CROPS AGAINST HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-13 | — | — | WO | disclosed |
| EP-0431545-A2 | Selectif herbicidal agent and fungicidal agent | Hoechst Schering AgrEvo GmbH (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0417626-A2 | Plant protection agents containing N-arylhydrazones and N-arylhydrazones | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0409118-A1 | Pyrazolines and their use as antidotes | Hoechst Schering AgrEvo GmbH (DE) | 1991-01-23 | — | — | EP | disclosed |
| EP-0333131-A1 | Plant protective agent based on pyrazolecarboxylic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-20 | — | — | EP | disclosed |