Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 4/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562934 | 0.77 | VDR (0.43) | VDRMRGPRX4FFAR1NR4A2F2 | |
| SCHEMBL7608339 | 0.72 | VDR (0.42) | VDRMRGPRX4FFAR1FFAR4 | |
| SCHEMBL6564829 | 0.71 | VDR (0.50) | VDRMRGPRX4FFAR1CYP4F2CYP4A11 | |
| SCHEMBL7613338 | 0.70 | VDR (0.44) | VDRMRGPRX4FFAR1NR4A2F2 | |
| SCHEMBL7608503 | 0.70 | VDR (0.44) | VDRMRGPRX4FFAR1NR4A2F2 | |
| SCHEMBL6563099 | 0.70 | VDR (0.49) | VDRMRGPRX4FFAR1NR4A2F2 | |
| SCHEMBL6566409 | 0.70 | VDR (0.49) | VDRMRGPRX4FFAR1NR4A2F2 | |
| SCHEMBL7611180 | 0.70 | MRGPRX4 (0.44) | MRGPRX4FFAR1NR4A2PTGER4AKR1B1 | |
| SCHEMBL6564905 | 0.70 | VDR (0.51) | VDRMRGPRX4FFAR1NR4A2TSHR | |
| SCHEMBL7606366 | 0.70 | VDR (0.44) | VDRMRGPRX4FFAR1NR4A2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |