Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042563 | 0.89 | VDR (0.42) | VDRMRGPRX4MAOBNR4A2FFAR1 | |
| SCHEMBL6562943 | 0.84 | FFAR1 (0.40) | MRGPRX4MAOBFFAR1F9F10 | |
| SCHEMBL7607829 | 0.77 | FFAR1 (0.33) | VDRFFAR1 | |
| SCHEMBL7608533 | 0.77 | VDR (0.42) | VDRMRGPRX4NR4A2F2FFAR1 | |
| SCHEMBL7606366 | 0.77 | VDR (0.44) | VDRMRGPRX4MAOBNR4A2FFAR1 | |
| SCHEMBL7608339 | 0.76 | VDR (0.42) | VDRMRGPRX4MAOBFFAR1PPARD | |
| SCHEMBL7608503 | 0.76 | VDR (0.44) | VDRMRGPRX4MAOBNR4A2F2 | |
| SCHEMBL7613338 | 0.76 | VDR (0.44) | VDRMRGPRX4NR4A2F2FFAR1 | |
| SCHEMBL7604645 | 0.74 | VDR (0.42) | VDRMRGPRX4MAOBFFAR1PPARD | |
| SCHEMBL7608336 | 0.74 | VDR (0.42) | VDRMRGPRX4FFAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| CN-1423627-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2003-06-11 | — | — | CN | claimed |
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |