SCHEMBL7608604

SCHEMBL7608604

CCCCc1nc2cc([N+](=O)[O-])ccc2[nH]1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.67
KCNJ1 P48048 2/20 0.67
ALDH1A1 P00352 2/20 0.67
LMNA P02545 2/20 0.67
MAPT P10636 2/20 0.67
PKM P14618 1/20 0.61
RIPK1 Q13546 2/20 0.51
CCNT1 O60563 1/20 0.51
CDK9 P50750 1/20 0.51
GAA P10253 1/20 0.48
HPGD P15428 2/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPBWR1 P48145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9721024 0.95 KDM4E (0.64) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL783686 0.95 KDM4E (0.64) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL9720944 0.95 KDM4E (0.64) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL8601352 0.92 KDM4E (0.80) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL9642123 0.92 MAPT (0.78) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL7033532 0.90 MAPT (0.72) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL7608611 0.89 KDM4E (0.85) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL6753972 0.86 GAA (0.64) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL1250581 0.85 KDM4E (0.82) KDM4EKCNJ1ALDH1A1LMNAMAPT
SCHEMBL7099247 0.84 KDM4E (0.53) KDM4EKCNJ1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5173130-A Immersing copper or alloy to be soldered in an aqueous solution containing a 2-alkylbenzimidazole and an organic acid to form a corrosion and heat resistant protective coating SHIKOKU CHEMICALS CORPORATION (JP) 1992-12-22 US claimed
CN-1095623-C Organic-metallic composite coating for copper surface protection IBM (US) 2002-12-04 CN disclosed
US-20020067486-A1 Solderability assessment AMERICAN COMPETITIVENESS INSTITUTE 2002-06-06 US disclosed
US-5960251-A Organic-metallic composite coating for copper surface protection INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-09-28 US disclosed
US-5864043-A CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST KARL THOMAE GMBH (DE) 1999-01-26 US disclosed
CN-1188589-A Organic-metal composite coating for copper surface protection IBM (US) 1998-07-22 CN disclosed
WO-1997039610-A1 ORGANIC-METALLIC COMPOSITE COATING FOR COPPER SURFACE PROTECTION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-10-23 WO disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed
US-5519138-A ANGIOTENSIN ANTAGONIST DR. KARL THOMAE GMBH (DE) 1996-05-21 US disclosed
EP-0392317-B1 Benzimidazoles, drugs containing these compounds and process for their preparation THOMAE GMBH DR K (DE) 1996-01-03 EP disclosed
CN-1029961-C Benzimidazole derivatives, their prodn. and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-10-11 CN disclosed
EP-0425921-B1 Benzimidazole derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-08-09 EP disclosed
US-5250554-A Cardiovascular disorders TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-05 US disclosed
EP-0529253-A1 Phenylalkylderivatives, compounds containing them and process for their fabrication Dr. Karl Thomae GmbH (DE) 1993-03-03 EP disclosed
US-5173130-A Immersing copper or alloy to be soldered in an aqueous solution containing a 2-alkylbenzimidazole and an organic acid to form a corrosion and heat resistant protective coating SHIKOKU CHEMICALS CORPORATION (JP) 1992-12-22 US disclosed
US-5128356-A Angiotensin antagonist; cardiovascular disorders TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-07 US disclosed
EP-0428383-A1 Process for surface treatment of copper and copper alloy SHIKOKU CHEMICALS CORPORATION (JP) 1991-05-22 EP disclosed
CN-1051355-A Benzimidizole derivatives, its production method and application thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1991-05-15 CN disclosed
EP-0425921-A1 Benzimidazole derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-05-08 EP disclosed
EP-0392317-A2 Benzimidazoles, drugs containing these compounds and process for their preparation Dr. Karl Thomae GmbH (DE) 1990-10-17 EP disclosed