Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611608 | 0.87 | FAAH (0.41) | ALDH1A1KMT2AEGLN2FTOFAAH | |
| SCHEMBL7606839 | 0.85 | FAAH (0.47) | KMT2AFAAHHPGDHSD17B10 | |
| SCHEMBL7607577 | 0.84 | KDM4E (0.45) | FAAHMAPK1 | |
| SCHEMBL7610436 | 0.83 | EGLN2 (0.38) | ALDH1A1KMT2AEGLN2FTOMEN1 | |
| SCHEMBL7614301 | 0.83 | KDM4E (0.47) | ALDH1A1FAAH | |
| SCHEMBL7609545 | 0.83 | KDM4E (0.47) | ALDH1A1FAAH | |
| SCHEMBL7605070 | 0.83 | KDM4E (0.47) | ALDH1A1FAAH | |
| SCHEMBL7614162 | 0.83 | KDM4E (0.47) | ALDH1A1FAAH | |
| SCHEMBL7605129 | 0.83 | KDM4E (0.47) | ALDH1A1FAAH | |
| SCHEMBL7605083 | 0.83 | KDM4E (0.47) | ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846685-B1 | 3-Hydroxypyridine-2-carboxylic acid amide esters, their preparation and their use as medicaments | HOECHST AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0846685-A1 | 3-Hydroxypyridine-2-carboxylic acid amide esters, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-10 | — | — | EP | disclosed |