SCHEMBL7608796

SCHEMBL7608796

COc1ccc(C(CNC(Oc2ccc(O)c(NS(C)(=O)=O)c2)C(C)O)c2ccc(OC)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.60
ADRB2 P07550 2/20 0.54
ADRB1 P08588 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7608479 0.88 ADRB3 (0.48) ADRB3ADRB2ADRB1
SCHEMBL7611182 0.81 GAA (0.44) ADRB3ADRB2ADRB1
SCHEMBL7609836 0.81 ADRB3 (0.47) ADRB3ADRB2ADRB1
SCHEMBL7638524 0.79 ADRB3 (0.78) ADRB3
SCHEMBL7611056 0.79 ADRB3 (0.45) ADRB3ADRB2ADRB1
SCHEMBL7605258 0.79 ADRB3 (0.47) ADRB3
SCHEMBL7608782 0.78 ADRB3 (0.75) ADRB3ADRB2ADRB1
SCHEMBL7610435 0.77 ADRB2 (0.52) ADRB3ADRB2ADRB1
Hydrochloric Acid SCHEMBL6322184 0.77 ADRB3 (0.74) ADRB3
SCHEMBL7607779 0.77 ADRB2 (0.56) ADRB3ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1230210-A1 AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-08-14 EP disclosed
WO-2001036375-A1 AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-25 WO disclosed