Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610449 | 0.94 | GAA (0.42) | ADRB3ADRB2ADRB1GAAHSD17B10 | |
| SCHEMBL7605258 | 0.92 | ADRB3 (0.47) | ADRB3GAAHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL7608479 | 0.91 | ADRB3 (0.48) | ADRB3ADRB2ADRB1GAAHSD17B10 | |
| SCHEMBL7611182 | 0.84 | GAA (0.44) | ADRB3ADRB2ADRB1GAAHSD17B10 | |
| SCHEMBL7605384 | 0.82 | ADRB3 (0.51) | ADRB3ADRB2ADRB1GAAHSD17B10 | |
| SCHEMBL7607779 | 0.82 | ADRB2 (0.56) | ADRB3ADRB2ADRB1ALDH1A1MITF | |
| SCHEMBL7611056 | 0.81 | ADRB3 (0.45) | ADRB3ADRB2ADRB1GAAALDH1A1 | |
| SCHEMBL7608796 | 0.81 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7605372 | 0.80 | ADRB3 (0.62) | ADRB3 | |
| Hydrochloric Acid SCHEMBL7608327 | 0.80 | ADRB3 (0.61) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |