Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615502 | 0.93 | CRHR1 (0.60) | CRHR1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL7228514 | 0.83 | CRHR1 (0.61) | CRHR1KDM4ETDP1 | |
| SCHEMBL5599396 | 0.78 | CRHR1 (0.53) | CRHR1KDM4EMEN1KMT2A | |
| SCHEMBL5599813 | 0.78 | CRHR1 (0.53) | CRHR1KDM4E | |
| SCHEMBL7220332 | 0.77 | CRHR1 (0.49) | CRHR1KDM4E | |
| SCHEMBL7226595 | 0.77 | CRHR1 (0.51) | CRHR1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL6306407 | 0.75 | CRHR1 (0.60) | CRHR1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL5600092 | 0.75 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL5599426 | 0.75 | CRHR1 (0.57) | CRHR1MEN1KMT2A | |
| SCHEMBL7226248 | 0.73 | CRHR1 (0.58) | CRHR1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432989-B1 | TREATING SLEEP DISORDERS | PFIZER INC | 2002-08-13 | — | — | US | disclosed |