Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137969 | 1.00 | ITGA4 (0.50) | ITGA4ITGB7KLK5ATMPOLB | |
| SCHEMBL13163803 | 1.00 | ITGA4 (0.50) | ITGA4ITGB7KLK5ATMPOLB | |
| SCHEMBL1937057 | 0.94 | ABCB1 (0.46) | ITGA4ITGB7KLK5ATMPOLB | |
| SCHEMBL8724334 | 0.88 | ITGA4 (0.49) | ITGA4ITGB7KLK5ATMCTSS | |
| SCHEMBL8724329 | 0.88 | ITGA4 (0.49) | ITGA4ITGB7KLK5ATMCTSS | |
| SCHEMBL12600955 | 0.88 | ITGA4 (0.49) | ITGA4ITGB7KLK5ATMCTSS | |
| SCHEMBL11651226 | 0.87 | ATM (0.45) | ITGA4ITGB7ATMCTSSCTSL | |
| SCHEMBL9321962 | 0.87 | ATM (0.45) | ITGA4ITGB7ATMCTSSCTSL | |
| SCHEMBL8392929 | 0.87 | ATM (0.45) | ITGA4ITGB7ATMCTSSCTSL | |
| SCHEMBL15702033 | 0.86 | ITGA4 (0.38) | ITGA4ITGB7KLK5ATMCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020142967-A1 | Thrombin inhibitors | ADANG A E P (NL) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142967-A1 | Thrombin inhibitors | SERPINC1, DAO, CTRL | ITGA4 294/4885ITGB7 1376/4885KLK5 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.