Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608253 | 1.00 | ADRB3 (0.45) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7611523 | 0.86 | L3MBTL1 (0.41) | ADRB3L3MBTL1ADRB2ALDH1A1NPC1 | |
| SCHEMBL7608285 | 0.85 | ADRB3 (0.40) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7609423 | 0.85 | ADRB3 (0.40) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7656679 | 0.84 | ADRB3 (0.44) | ADRB3ADRB2 | |
| SCHEMBL6074837 | 0.84 | ADRB3 (0.50) | ADRB3NR3C1ADRB2 | |
| SCHEMBL7606877 | 0.84 | ADRB3 (0.44) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7608520 | 0.83 | FFAR1 (0.40) | L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7605273 | 0.82 | ADRB3 (0.44) | ADRB3ADRB2KCNH2 | |
| SCHEMBL7610055 | 0.80 | ADRB3 (0.40) | ADRB3NR3C1ARADRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |