Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609423 | 1.00 | ADRB3 (0.40) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7611531 | 0.86 | ESR1 (0.38) | HPGDNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL7609387 | 0.85 | ADRB3 (0.45) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7608253 | 0.85 | ADRB3 (0.45) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7606900 | 0.84 | ADRB3 (0.38) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7608529 | 0.83 | FFAR1 (0.40) | HPGDNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL7604970 | 0.83 | NR3C1 (0.43) | ADRB3NR3C1ARPGRNR3C2 | |
| SCHEMBL7605292 | 0.82 | ACP1 (0.42) | ADRB3NR3C1ALDH1A1CYP19A1GAA | |
| SCHEMBL7610067 | 0.81 | AR (0.38) | ADRB3NR3C1ARALDH1A1CYP19A1 | |
| SCHEMBL7614703 | 0.77 | SMN1; SMN2 (0.41) | NR3C1ARNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |