Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854732 | 0.82 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4557939 | 0.81 | NPC1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL714734 | 0.78 | ALDH1A1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL5437344 | 0.78 | ALDH1A1 (0.37) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6142471 | 0.78 | POLB (0.31) | — | |
| SCHEMBL4650969 | 0.77 | ALDH1A1 (0.34) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL40372 | 0.71 | ALDH1A1 (0.45) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29459210 | 0.71 | ALDH1A1 (0.45) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL7612692 | 0.71 | NPC1 (0.32) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Lithium SCHEMBL6552341 | 0.69 | ALDH1A1 (0.44) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524624-B1 | Use of organometallic flurorenyl compounds. | PHILLIPS PETROLEUM CO (US) | 2002-05-15 | — | — | EP | claimed |
| US-6072085-A | COMBINING SUBSTRATE IMINE, NUCLEOPHILIC ACTIVATOR, SILANE, METAL CATALYST, WHEREIN CATALYST CATALYZES REDUCTION OF IMINE BY HYDROSILATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0726271-B1 | Organoaluminoxy product, catalyst systems, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5670589-A | COORDINATION POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0726271-A1 | Organoaluminoxy product, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |