Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430052 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL25633605 | 0.83 | ELANE (0.36) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL5820431 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL3888554 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL29459210 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL40372 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL5820049 | 0.81 | KIF11 (0.38) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL6552336 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| Lithium SCHEMBL6552341 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL7526556 | 0.80 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230128-B2 | Organometallic fluorenyl compounds, preparations, and use | PHILLIPS POTROLEUM COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060122344-A1 | Organometallic Fluorenyl Compounds, Preparations, and Use | PHILLIPS PETROLEUM COMPANY (US) | 2006-06-08 | — | — | US | disclosed |
| US-6420579-B1 | SILYL, GERMANIUM OR TIN RADICALS WITH TITANIUM, ZIRCONIUM, HAFNIUM, VANADIUM, NIOBIUM AND TANTALUM METALS | PHILLIPS PETROLEUM COMPANY | 2002-07-16 | — | — | US | disclosed |
| US-6403734-B1 | POLYMERIZING ALPHA-OLEFIN BY CONTACTING WITH CATALYST SYSTEM COMPRISING BRIDGED FLUORENYL METALLOCENE CONTAINING METAL OF GROUP 4 OR 5 AND SUITABLE COCATALYST | PHILLIPS PETROLEUM COMPANY | 2002-06-11 | — | — | US | disclosed |
| EP-0524624-B1 | Use of organometallic flurorenyl compounds. | PHILLIPS PETROLEUM CO (US) | 2002-05-15 | — | — | EP | disclosed |
| US-6346635-B1 | FORMING A COMPLEX, DEPROTINATION, SILATION AND COMPLEXING | BASELL POLYOLEFINE GMBH (DE) | 2002-02-12 | — | — | US | disclosed |
| US-6162936-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 2000-12-19 | — | — | US | disclosed |
| EP-0512554-B1 | Method for making cyclopentadiene type compounds | PHILLIPS PETROLEUM CO (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5541351-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| CN-1030068-C | Cyclopentadiene type compound and process for producing the same | PHILLIPS PETROLEUM CO (US) | 1995-10-18 | — | — | CN | disclosed |
| US-5436305-A | Preparing polymer catalysts by reaction of alkali metal alkyl and fluorenyl in solvent | PHILLIPS PETROLEUM COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-5420320-A | Method for preparing cyclopentadienyl-type ligands and metallocene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5406013-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5393911-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5191132-A | CYCLOPENTADIENE TYPE COMPOUNDS AND METHOD FOR MAKING | PHILLIPS PETROLEUM COMPANY (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0524624-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-27 | — | — | EP | disclosed |
| CN-1066440-A | Cyclopeutadiene type compounds and preparation method thereof | PHILLIPS PETROLEUM CO (US) | 1992-11-25 | — | — | CN | disclosed |
| EP-0512554-A2 | Cyclopetadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1992-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122344-A1 | Organometallic Fluorenyl Compounds, Preparations, and Use | HMBS, FDPS, SOD1 | ALDH1A1 790/4885NPC1 1718/4885RAB9A 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.