Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135728 | 0.83 | LTA4H (0.52) | TSHRLTA4HCA12CA1CA2 | |
| SCHEMBL7849257 | 0.83 | LTA4H (0.50) | NQO1LTA4HKDM4EALDH1A1CA12 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.80 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.80 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL6903801 | 0.79 | NR5A1 (0.56) | TSHRLTA4HMAPTGAANPC1 | |
| SCHEMBL1551402 | 0.77 | NQO1 (0.64) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL11794798 | 0.77 | NQO1 (0.93) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL7848207 | 0.77 | MAPT (0.44) | TSHRKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6545404 | 0.75 | TP53 (0.53) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL27616183 | 0.75 | NQO1 (0.88) | NQO1TSHRTDP1LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11012217-A | — | — | None | — | — | JP | disclosed |
| EP-0790251-B1 | Preparation and use of (3-alkoxyphenyl) magnesium chlorides | GRUENENTHAL GMBH (DE) | 2002-12-04 | — | — | EP | disclosed |
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| JP-H1112217-A | BUTANE DERIVATIVE | SUMITOMO CHEM CO LTD | 1999-01-19 | — | — | JP | disclosed |
| US-5852216-A | Preparation and use of (3-alkoxy-phenyl) magnesium chlorides | GRUENENTHAL GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0790251-A2 | Preparation and use of (3-alkoxyphenyl) magnesium chlorides | Grünenthal GmbH (DE) | 1997-08-20 | — | — | EP | disclosed |