Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 8/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964228 | 1.00 | BRD4 (0.45) | BRD4CREBBPPBRM1MAOAMAOB | |
| SCHEMBL28813644 | 0.81 | MAOA (0.59) | BRD4CREBBPPBRM1MAOAMAOB | |
| SCHEMBL31398716 | 0.81 | MAOA (0.50) | BRD4CREBBPMAOAMAOBKDM4E | |
| SCHEMBL4596846 | 0.76 | KDM4E (0.43) | BRD4CREBBPMAOAMAOBKDM4E | |
| SCHEMBL7947753 | 0.74 | KDM4E (0.47) | BRD4CREBBPMAOAMAOBKDM4E | |
| SCHEMBL16432621 | 0.74 | AKR1B1 (0.40) | BRD4CREBBPPBRM1MAOAMAOB | |
| SCHEMBL9819236 | 0.73 | MAOB (0.61) | BRD4CREBBPPBRM1MAOBKDM4E | |
| SCHEMBL69392 | 0.73 | MAOB (0.61) | BRD4CREBBPPBRM1MAOBKDM4E | |
| SCHEMBL15147107 | 0.73 | MAOB (0.61) | BRD4CREBBPPBRM1MAOBKDM4E | |
| SCHEMBL31217595 | 0.73 | BCHE (0.40) | BRD4CREBBPMAOAMAOBPOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1166791-A2 | Antipsoriatic compositions comprising an asphodelus extract, method of making, and method of using | Moady, Said (US) | 2002-01-02 | — | — | EP | disclosed |