SCHEMBL7609636

SCHEMBL7609636

CO/N=C(C(/C)=N/O)\c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 2/20 0.37
POLB P06746 2/20 0.37
HPGD P15428 1/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
GSK3B P49841 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8501552 1.00 TRPA1 (0.43) TRPA1ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL7205061 0.84 LMNA (0.40) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL7205062 0.84 LMNA (0.40) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL7859294 0.82 SMN1; SMN2 (0.43) TRPA1ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL8499333 0.82 SMN1; SMN2 (0.43) TRPA1ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL8720211 0.82 GSK3B (0.50) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL8460844 0.81 GAA (0.41) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL5597826 0.81 GAA (0.41) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL6700689 0.80 CYP1A2 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL6700693 0.80 CYP1A2 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984686-B1 METHOD FOR COMBATING HARMFUL FUNGI BASF AG (DE) 2002-02-20 EP disclosed
EP-1137627-A1 PROCESS FOR THE PREPARATION OF STROBILURIN INTERMEDIATES Bayer Aktiengesellschaft (DE) 2001-10-04 EP disclosed
US-6255352-B1 TREATING FUNGI, PLANTS, SOIL OR SEEDS WITH DOSAGE OF A BISOXIME DERIVATIVE BASF AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed
EP-0820435-B1 METHOD OF PREPARING ESSENTIALLY PURE ISOMERS OF ALPHA-BIS-OXIMES BASF AG (DE) 2001-05-16 EP disclosed
WO-2000034229-A1 PROCESS FOR THE PREPARATION OF STROBILURIN INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 2000-06-15 WO disclosed
EP-0984686-A1 METHOD FOR COMBATING HARMFUL FUNGI BASF AKTIENGESELLSCHAFT (DE) 2000-03-15 EP disclosed
US-5929279-A Preparation of Bisoximes BASF AKTIENGESELLSCHAFT (DE) 1999-07-27 US disclosed
WO-1998053682-A1 METHOD FOR COMBATING HARMFUL FUNGI BASF AKTIENGESELLSCHAFT (DE) 1998-12-03 WO disclosed
EP-0820435-A1 METHOD OF PREPARING ESSENTIALLY PURE ISOMERS OF $g(a)-BIS-OXIMES BASF AKTIENGESELLSCHAFT (DE) 1998-01-28 EP disclosed
WO-1996032373-A1 METHOD OF PREPARING ESSENTIALLY PURE ISOMERS OF α-BIS-OXIMES BASF AKTIENGESELLSCHAFT (DE) 1996-10-17 WO disclosed