Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.95 |
| ▸ | RAB9A | P51151 | 6/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.95 |
| ▸ | TSHR | P16473 | 2/20 | 0.95 |
| ▸ | TP53 | P04637 | 1/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.95 |
| ▸ | PTPRC | P08575 | 4/20 | 0.91 |
| ▸ | MEN1 | O00255 | 3/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | S100A4 | P26447 | 3/20 | 0.91 |
| ▸ | LMNA | P02545 | 3/20 | 0.91 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.91 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.91 |
| ▸ | APAF1 | O14727 | 2/20 | 0.91 |
| ▸ | TDP2 | O95551 | 2/20 | 0.91 |
| ▸ | POLB | P06746 | 2/20 | 0.91 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30482647 | 1.00 | NPC1 (0.95) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL31615519 | 1.00 | NPC1 (0.95) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| Anthraquinone SCHEMBL23363689 | 0.98 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL40960 | 0.98 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL31290097 | 0.98 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL30043508 | 0.95 | PTPRC (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| Benzene SCHEMBL28832927 | 0.95 | NPC1 (0.95) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1143226 | 0.95 | PTPRC (0.91) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL2599178 | 0.95 | PTPRC (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL6262683 | 0.91 | PTPRC (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834119-A | Method for synthesizing bisphenol compound by catalysis of supported ionic liquid | 郑州中科新兴产业技术研究院 | 2024-10-25 | — | — | CN | claimed |
| CN-117756619-A | 3-bromofluorenone and preparation method thereof | 维思普新材料（苏州）有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-111885914-A | Compositions and methods for producing expanded hematopoietic stem cells using fluorene derivatives | 投资健康有限责任公司 | 2020-11-03 | — | — | CN | claimed |
| EP-3700334-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | Transfusion Health, LLC (US) | 2020-09-02 | — | — | EP | claimed |
| US-20200255371-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | IMMUNEBRIDGE LLC | 2020-08-13 | — | — | US | claimed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | claimed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | claimed |
| EP-0410287-B1 | Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups | CONSIGLIO NAZIONALE RICERCHE (IT) | 1995-11-02 | — | — | EP | claimed |
| EP-0430434-B1 | Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds | ZENECA LTD (GB) | 1994-09-14 | — | — | EP | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| EP-0430434-A2 | Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds | ZENECA LIMITED (GB) | 1991-06-05 | — | — | EP | claimed |
| EP-0410287-A2 | Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1991-01-30 | — | — | EP | claimed |
| JP-60084253-A | — | — | None | — | — | JP | disclosed |
| JP-62059934-A | — | — | None | — | — | JP | disclosed |
| US-20260139710-A1 | BEARING DEVICE, METHOD OF MANUFACTURING BEARING DEVICE, HARD DISK DRIVE DEVICE, AND MOTOR | MINEBEA MITSUMI INC (JP) | 2026-05-21 | — | — | US | disclosed |
| CN-122062050-A | Bearing device, method for manufacturing bearing device, hard disk drive device, and motor | 美蓓亚三美株式会社 | 2026-05-19 | — | — | CN | disclosed |
| EP-0124891-A2 | Antimutagenic agent and method of inactivating the mutagenicity of foods and beverages by using said agent | SUNTORY LIMITED (JP) | 1984-11-14 | — | — | EP | disclosed |
| US-4436745-A | TETRACYCLIC SPIROHYDANTOINS | ALCON LABORATORIES, INC. (US) | 1984-03-13 | — | — | US | disclosed |
| WO-1983003543-A1 | METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS | ALCON LAB INC (US) | 1983-10-27 | — | — | WO | disclosed |
| EP-0092385-A2 | Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds | ALCON LABORATORIES, INC. (US) | 1983-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255371-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | FLI1, MCL1, HCLS1 | NPC1 709/4885RAB9A 775/4885SMN1; SMN2 544/4885 |
| US-20260139710-A1 | BEARING DEVICE, METHOD OF MANUFACTURING BEARING DEVICE, HARD DISK DRIVE DEVICE, AND MOTOR | ZW10, SOD1, EED | NPC1 4386/4885RAB9A 489/4885SMN1; SMN2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.