Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564968 | 0.85 | CES2 (0.37) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6564975 | 0.85 | CES2 (0.37) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6564973 | 0.85 | CES2 (0.37) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6566256 | 0.77 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6566251 | 0.77 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6566254 | 0.77 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL27488888 | 0.75 | CES2 (0.40) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6562893 | 0.75 | CES2 (0.46) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6562909 | 0.75 | CES2 (0.46) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6562903 | 0.75 | CES2 (0.46) | CES2CES1ALDH1A1LMNAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |