Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTA1 | P08263 | 6/20 | 0.65 |
| ▸ | GSTP1 | P09211 | 6/20 | 0.65 |
| ▸ | PTPRC | P08575 | 4/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | PTPRB | P23467 | 4/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.58 |
| ▸ | CD69 | Q07108 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
| ▸ | CD14 | P08571 | 2/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761363 | 0.93 | GSTA1 (0.67) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856732 | 0.91 | GSTA1 (0.67) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL30702676 | 0.91 | GSTA1 (0.57) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL6067606 | 0.91 | GSTA1 (0.57) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL31326111 | 0.81 | GSTA1 (0.56) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856857 | 0.81 | GSTA1 (0.56) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL19726834 | 0.81 | GSTA1 (0.64) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856718 | 0.81 | GSTA1 (0.64) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL23931194 | 0.80 | GSTA1 (0.58) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856777 | 0.80 | GSTA1 (0.63) | GSTA1GSTP1PTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307116-B1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | CENTRE NAT RECH SCIENT (FR) | 2012-03-21 | — | — | EP | disclosed |
| EP-2307116-A1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | Centre National de la Recherche Scientifique - CNRS (FR) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009144419-A1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2009-12-03 | — | — | WO | disclosed |