Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTA1 | P08263 | 6/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 6/20 | 0.56 |
| ▸ | PTPRC | P08575 | 4/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.56 |
| ▸ | PTPRB | P23467 | 4/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.56 |
| ▸ | CD69 | Q07108 | 2/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | CD14 | P08571 | 1/20 | 0.43 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.43 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326111 | 1.00 | GSTA1 (0.56) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856732 | 0.91 | GSTA1 (0.67) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL6067606 | 0.89 | GSTA1 (0.57) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL30702676 | 0.89 | GSTA1 (0.57) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL5021866 | 0.88 | GSTA1 (0.51) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL6202528 | 0.87 | PTPRC (0.53) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL6203943 | 0.85 | GSTA1 (0.46) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856718 | 0.83 | GSTA1 (0.64) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL19726834 | 0.83 | GSTA1 (0.64) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856777 | 0.82 | GSTA1 (0.63) | GSTA1GSTP1PTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028676-A1 | Molecular Actuators, and Methods of Use Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| US-7658868-B2 | Class of molecular actuators where bulk actuation mechanisms such as ion intercalation are enhanced by controllable single molecule conformational rearrangements offers promise in exhibiting large active strains at moderate stresses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | NOD2, PIEZO1, TPR | GSTA1 969/4885GSTP1 150/4885PTPRC 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.