Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7641612 | 0.98 | CYP19A1 (0.45) | CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7610946 | 0.77 | SLC6A2 (0.55) | SLC6A2 | |
| Hydrochloric Acid SCHEMBL7610918 | 0.75 | SLC6A2 (0.54) | SLC6A2 | |
| SCHEMBL5182572 | 0.74 | NR1H2 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7609760 | 0.74 | SLC6A2 (0.59) | SLC6A2 | |
| SCHEMBL7616449 | 0.74 | SLC6A2 (0.57) | SLC6A2 | |
| SCHEMBL9168266 | 0.74 | CYP2C19 (0.59) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL7616450 | 0.72 | SLC6A2 (0.58) | SLC6A2 | |
| Hydrochloric Acid SCHEMBL7610820 | 0.72 | SLC6A2 (0.56) | SLC6A2 | |
| SCHEMBL7613237 | 0.72 | SLC6A2 (0.58) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | claimed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | claimed |
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | claimed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | claimed |
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | disclosed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | disclosed |
| US-5194618-A | Cognition activators for memory enhancers | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| US-5039687-A | Learning enhancement, cognition activation | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5032599-A | Learning enhancement | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4792562-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| US-4752610-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0226099-A2 | N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1987-06-24 | — | — | EP | disclosed |