Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324370 | 0.86 | ADRB3 (0.75) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7610557 | 0.85 | ADRB3 (0.74) | ADRB3ABCB1MEN1OPRM1OPRD1 | |
| SCHEMBL6326499 | 0.80 | ADRB3 (0.73) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7768578 | 0.80 | ADRB3 (0.65) | ADRB3ABCB1MEN1OPRM1OPRD1 | |
| SCHEMBL7609817 | 0.80 | ADRB3 (0.61) | ADRB3ABCB1MEN1OPRM1OPRD1 | |
| SCHEMBL7607621 | 0.79 | ADRB2 (0.68) | ADRB3MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7614540 | 0.79 | ADRB3 (0.57) | ADRB3ABCB1MEN1OPRM1OPRD1 | |
| SCHEMBL7607740 | 0.79 | ADRB3 (0.57) | ADRB3ABCB1MEN1OPRM1OPRD1 | |
| SCHEMBL7609934 | 0.79 | ADRB3 (0.43) | ADRB3KMT2AADRB2ADRB1 | |
| SCHEMBL7605251 | 0.78 | ADRB3 (0.59) | ADRB3MEN1KMT2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |