Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610581 | 0.85 | ADRB2 (0.45) | ADRB3CNR1CNR2ADRB2ADRB1 | |
| SCHEMBL7609836 | 0.80 | ADRB3 (0.47) | ADRB3CNR1CNR2ADRB2ADRB1 | |
| SCHEMBL7607623 | 0.79 | ADRB3 (0.44) | ADRB3CNR1CNR2ADRB2ADRB1 | |
| SCHEMBL7609925 | 0.79 | ADRB3 (0.56) | ADRB3ADRB2ADRB1KMT2A | |
| SCHEMBL7607779 | 0.78 | ADRB2 (0.56) | ADRB3CNR1CNR2ADRB2ADRB1 | |
| SCHEMBL7605258 | 0.78 | ADRB3 (0.47) | ADRB3MITFALDH1A1LMNAMAPT | |
| SCHEMBL7608796 | 0.77 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7610781 | 0.76 | ADRB2 (0.40) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7610449 | 0.73 | GAA (0.42) | ADRB3ADRB2ADRB1MITFALDH1A1 | |
| SCHEMBL7606228 | 0.71 | ADRB2 (0.48) | ADRB3CNR1CNR2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |