Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538571 | 0.83 | CES2 (0.53) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL7604796 | 0.82 | MAPT (0.47) | CES2CES1PTPN1 | |
| SCHEMBL6942780 | 0.81 | CES2 (0.52) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL2322081 | 0.80 | CES1 (0.59) | CES2CES1GSK3BMEN1TSHR | |
| SCHEMBL7798781 | 0.78 | CES2 (0.61) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL8235165 | 0.78 | CES2 (0.61) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL23172558 | 0.77 | CES2 (0.67) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL1078685 | 0.77 | CES1 (0.67) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL21387720 | 0.76 | CES2 (0.59) | CES2CES1SRD5A2NR4A1NR4A2 | |
| SCHEMBL7806283 | 0.76 | CES2 (0.59) | CES2CES1SRD5A2NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026154-B1 | Preparation process of difluoroacetophenone derivatives | SSP CO LTD (JP) | 2002-09-04 | — | — | EP | disclosed |
| EP-0780380-B1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6229049-B1 | COUPLING AN ALKYLTHIODIFLUOROACETIC ACID ESTER DERIVATIVE TO A HALOBENZENE DERIVATIVE AS AN INTERMEDIATE FOR 'TRIAZOLES' FUNGICIDES; TREATING MYCOTIC INFECTIOUS DISEASES | SSP CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| EP-1026154-A2 | Preparation process of difluoroacetophenone derivatives | SSP Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-6002028-A | FUNGICIDES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5986144-A | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5945438-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0780380-A1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |