Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609999 | 0.83 | CES2 (0.55) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL7798781 | 0.80 | CES2 (0.61) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL8235165 | 0.80 | CES2 (0.61) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL7806283 | 0.79 | CES2 (0.59) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL8821889 | 0.76 | CES1 (0.50) | CES2CES1MEN1HPGDTSHR | |
| SCHEMBL23172558 | 0.76 | CES2 (0.67) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL1078685 | 0.76 | CES1 (0.67) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL26054729 | 0.76 | CES2 (0.55) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL21387720 | 0.75 | CES2 (0.59) | CES2CES1TRPV1SRD5A2NR4A1 | |
| SCHEMBL29137235 | 0.74 | CES2 (0.64) | CES2CES1TRPV1SRD5A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435081-B1 | Triazole derivatives | SS PHARMACEUTICAL CO (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5147886-A | Skin disorders; urogenital,respiratory systems | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| EP-0435081-A2 | Triazole derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |