Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115891 | 0.83 | HPGD (0.57) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL37698 | 0.83 | HPGD (0.54) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL3625220 | 0.82 | FTO (0.58) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL17515090 | 0.79 | ALDH1A1 (0.55) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL273427 | 0.78 | FTO (0.59) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL9474742 | 0.77 | FTO (0.58) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL213292 | 0.77 | HPGD (0.53) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL30887310 | 0.76 | ALDH1A1 (0.63) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL134733 | 0.76 | ALDH1A1 (0.63) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL30887311 | 0.76 | ALDH1A1 (0.63) | HPGDALDH1A1CYP2C9ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432640-B1 | COMPARING THE LEVELS OF TRANSCRIPTION OF RNA TRANSCRIPTS FROM CELLS OF KNOWN NORMAL TISSUE AND SUSPECTED MUTANT OR CANCER CELLS | THE JOHNS HOPKINS UNIVERSITY | 2002-08-13 | — | — | US | disclosed |
| US-20020055097-A1 | Comparing the levels of transcription of RNA transcripts from cells of known normal tissue and suspected mutant or cancer cells | JOHNS HOPKINS UNIVERSITY, THE | 2002-05-09 | — | — | US | disclosed |
| EP-1015624-A2 | P53-INDUCED APOPTOSIS | THE JOHNS HOPKINS UNIVERSITY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999014356-A2 | P53-INDUCED APOPTOSIS | THE JOHNS HOPKINS UNIVERSITY (US) | 1999-03-25 | — | — | WO | disclosed |