Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.41 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375068 | 1.00 | ADRB3 (0.45) | ADRB3PDPK1CTSAPKMALOX5 | |
| SCHEMBL20586652 | 0.85 | PLA2G4A (0.44) | ADRB3PDPK1CTSAALOX5KDM4E | |
| SCHEMBL16198433 | 0.82 | ANPEP (0.43) | ADRB3CTSALMNAPTPRBADAM17 | |
| SCHEMBL7269817 | 0.82 | HSPA1A (0.40) | ADRB3PDPK1CTSAPKMALOX5 | |
| SCHEMBL7269813 | 0.82 | HSPA1A (0.40) | ADRB3PDPK1CTSAPKMALOX5 | |
| SCHEMBL7269816 | 0.82 | HSPA1A (0.40) | ADRB3PDPK1CTSAPKMALOX5 | |
| SCHEMBL7269821 | 0.82 | HSPA1A (0.40) | ADRB3PDPK1CTSAPKMALOX5 | |
| SCHEMBL1952256 | 0.82 | PLA2G4A (0.52) | PLA2G4ALMNACES1L3MBTL1SMN1; SMN2 | |
| SCHEMBL19258127 | 0.82 | HSPA1A (0.40) | ADRB3PDPK1CTSAPKMALOX5 | |
| SCHEMBL7269324 | 0.82 | HSPA1A (0.40) | ADRB3PDPK1CTSAPKMALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1146535-C | Preparing method for azide derivatives | 卫材株式会社 | 2004-04-21 | — | — | CN | claimed |
| EP-0867431-B1 | Process for the preparation of azide derivatives | EISAI CO LTD (JP) | 2002-06-05 | — | — | EP | claimed |
| US-5986088-A | Process for the preparation of azide derivatives | EISAI CO., LTD. (JP) | 1999-11-16 | — | — | US | claimed |
| EP-0867431-A1 | Process for the preparation of azide derivatives | Eisai Chemical Co., Ltd. (JP) | 1998-09-30 | — | — | EP | claimed |
| CN-1194264-A | Preparing method for azide derivatives | EISAI CO LTD (JP) | 1998-09-30 | — | — | CN | claimed |
| EP-3607996-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2023-01-04 | — | — | EP | disclosed |
| EP-3388427-B1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | PF MEDICAMENT (FR) | 2022-01-19 | — | — | EP | disclosed |
| CN-108650882-B | Compositions for treating cancers expressing IGF-1R | 皮埃尔法布雷医药公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-106470708-B | Antibody-drug-conjugates and their use for the treatment of cancer | 皮埃尔法布雷医药公司 | 2019-12-31 | — | — | CN | disclosed |
| EP-3134124-B1 | IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2019-02-20 | — | — | EP | disclosed |
| EP-3368093-A1 | COMPOSITION FOR THE TREATMENT OF IGF-1R EXPRESSING CANCER | Pierre Fabre Medicament (FR) | 2018-09-05 | — | — | EP | disclosed |
| EP-2989088-B1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | PF MEDICAMENT (FR) | 2017-09-27 | — | — | EP | disclosed |
| WO-2017072196-A1 | COMPOSITION FOR THE TREATMENT OF IGF-1R EXPRESSING CANCER | PIERRE FABRE MEDICAMENT (FR) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017072196-A1 | COMPOSITION FOR THE TREATMENT OF IGF-1R EXPRESSING CANCER | PIERRE FABRE MEDICAMENT (FR) | 2017-05-04 | — | — | WO | disclosed |
| EP-2989086-A1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | Pierre Fabre Médicament (FR) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014174060-A1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | PIERRE FABRE MEDICAMENT (FR) | 2014-10-30 | — | — | WO | disclosed |
| CN-1146535-C | Preparing method for azide derivatives | 卫材株式会社 | 2004-04-21 | — | — | CN | disclosed |
| EP-0867431-B1 | Process for the preparation of azide derivatives | EISAI CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| CN-1194264-A | Preparing method for azide derivatives | EISAI CO LTD (JP) | 1998-09-30 | — | — | CN | disclosed |