Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595167 | 0.80 | APEX1 (0.41) | PDK2APEX1 | |
| SCHEMBL7612764 | 0.79 | MAPT (0.38) | PDK2APEX1 | |
| SCHEMBL7595150 | 0.79 | APEX1 (0.37) | APEX1 | |
| SCHEMBL7600206 | 0.79 | PDK2 (0.39) | PDK2 | |
| SCHEMBL7046510 | 0.78 | PDK2 (0.43) | PDK2APEX1 | |
| SCHEMBL7595652 | 0.77 | PDK2 (0.41) | PDK2 | |
| SCHEMBL7613371 | 0.75 | SIGMAR1 (0.47) | — | |
| SCHEMBL7597301 | 0.73 | KMT2A (0.39) | APEX1 | |
| SCHEMBL7599983 | 0.73 | PDK2 (0.37) | PDK2 | |
| SCHEMBL7599929 | 0.72 | TP53 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259492-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001047899-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES AS MTP INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |