Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442078 | 0.94 | NPSR1 (0.47) | NPSR1POLBKEAP1L3MBTL1FFAR1 | |
| SCHEMBL14370248 | 0.91 | NPSR1 (0.44) | NPSR1POLBKEAP1L3MBTL1FFAR1 | |
| SCHEMBL11321964 | 0.83 | NPSR1 (0.39) | NPSR1POLBKEAP1L3MBTL1FFAR1 | |
| SCHEMBL1607606 | 0.81 | IAPP (0.50) | NPSR1POLBFFAR1PTGER1PTGER4 | |
| SCHEMBL1262379 | 0.80 | MEN1 (0.46) | NPSR1KEAP1FFAR1SMN1; SMN2FFAR4 | |
| SCHEMBL11581221 | 0.79 | NPSR1 (0.48) | NPSR1POLBKEAP1L3MBTL1FFAR1 | |
| SCHEMBL9786032 | 0.79 | AOC3 (0.42) | NPSR1POLBFFAR1MAPK1HSD17B10 | |
| SCHEMBL878984 | 0.78 | KEAP1 (0.56) | NPSR1KEAP1FFAR1HDAC3MAPK1 | |
| SCHEMBL14409075 | 0.78 | LTB4R (0.38) | NPSR1POLBKEAP1L3MBTL1FFAR1 | |
| SCHEMBL27829688 | 0.77 | KEAP1 (0.48) | NPSR1KEAP1FFAR1PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223166-A1 | Linked cyclic polyamines with activity against hiv. | AnorMED Inc. (CA) | 2002-07-17 | — | — | EP | disclosed |