Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813698 | 0.78 | SMN1; SMN2 (0.49) | MAPK1MMP8SMN1; SMN2HIF1A | |
| SCHEMBL418231 | 0.71 | ALDH1A1 (0.46) | TDP1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12874139 | 0.69 | ALDH1A1 (0.46) | TDP1MAPK1MEN1KMT2A | |
| SCHEMBL6447831 | 0.69 | PPARA (0.39) | RENATMTSHRSMN1; SMN2HIF1A | |
| SCHEMBL7316106 | 0.69 | SMN1; SMN2 (0.46) | MAPK1MMP8SLC7A5SMN1; SMN2HIF1A | |
| SCHEMBL7609304 | 0.68 | ATM (0.56) | MAPK1RENATMAPPPSEN1 | |
| SCHEMBL26931972 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1A | |
| SCHEMBL7440502 | 0.68 | SMN1; SMN2 (0.45) | MAPK1ATMMMP8SLC7A5SMN1; SMN2 | |
| SCHEMBL11274358 | 0.67 | GRN (0.52) | MAPK1RENAPPPSEN1PSEN2 | |
| SCHEMBL7280321 | 0.67 | HIF1A (0.43) | MMP8SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128185-A1 | Pharmaceutical compounds | HAWAII, UNIVERSITY OF | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128185-A1 | Pharmaceutical compounds | XPO5, XPOT, XPO1 | MAPT 82/4885NPSR1 3139/4885TDP1 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.