Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047963 | 0.82 | PPARA (0.41) | MMECTSK | |
| SCHEMBL28000848 | 0.79 | MMP8 (0.55) | — | |
| SCHEMBL28000847 | 0.79 | MMP8 (0.55) | — | |
| SCHEMBL9702098 | 0.78 | FOLH1 (0.58) | — | |
| SCHEMBL5869993 | 0.77 | GRN (0.60) | GRNSORT1LTA4HMME | |
| SCHEMBL8609659 | 0.76 | SMN1; SMN2 (0.53) | MAPK1 | |
| SCHEMBL8609662 | 0.76 | SMN1; SMN2 (0.53) | MAPK1 | |
| SCHEMBL4937591 | 0.76 | SMN1; SMN2 (0.66) | CTSKMAPK1 | |
| SCHEMBL6464407 | 0.76 | SMN1; SMN2 (0.66) | CTSKMAPK1 | |
| SCHEMBL28951532 | 0.76 | CTSK (0.55) | GRNSORT1LTA4HMMECTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060422-A2 | Method for improving intestinal absorption of cephalosporin derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-09-22 | — | — | EP | disclosed |