SCHEMBL7611272

SCHEMBL7611272

CC1=Cc2ccccc2C1[Si](C)(C)C1C(C(C)C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617118 0.96
SCHEMBL7615118 0.94
SCHEMBL1452295 0.90 PDCD1 (0.30)
SCHEMBL5837020 0.90 ADRA2A (0.32) ADRA2AADRA2BADRA2C
SCHEMBL22462165 0.85 S1PR1 (0.31)
SCHEMBL5836990 0.85 ADRA2A (0.32) ADRA2AADRA2BADRA2C
SCHEMBL61908 0.83 PDCD1 (0.34) ADRA2AADRA2BADRA2C
SCHEMBL29366427 0.83 PDCD1 (0.34) ADRA2AADRA2BADRA2C
SCHEMBL1453690 0.83
SCHEMBL1454010 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834519-B1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN JAPAN POLYOLEFINS CO LTD (JP) 2002-03-06 EP disclosed
US-6121182-A A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES JAPAN POLYOLAFINS CO., LTD. (JP) 2000-09-19 US disclosed
EP-0834519-A1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN Japan Polyolefins Co., Ltd. (JP) 1998-04-08 EP disclosed