SCHEMBL61908

SCHEMBL61908

CC1=Cc2c(-c3ccccc3)cccc2C1[Si](C)(C)C1C(C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
ADRA2A P08913 2/20 0.33
ADRA2B P18089 2/20 0.33
ADRA2C P18825 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2B P41595 3/20 0.32
TMEM97 Q5BJF2 3/20 0.32
HTR1A P08908 2/20 0.32
HTR7 P34969 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366427 1.00 PDCD1 (0.34) PDCD1CD274ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL3822639 0.97 ADRA2A (0.34) PDCD1CD274ADRA2AADRA2BADRA2C
Dimethylamine SCHEMBL1453283 0.95 TDO2 (0.33) PDCD1CD274ADRA2AADRA2BADRA2C
SCHEMBL6056122 0.93 PDCD1 (0.30) PDCD1CD274
SCHEMBL16683341 0.93 PDCD1 (0.30) PDCD1CD274NTRK1NTRK3
SCHEMBL1452295 0.93 PDCD1 (0.30) PDCD1CD274
SCHEMBL7050759 0.92 PDCD1 (0.35) PDCD1CD274ADRA2AADRA2BADRA2C
SCHEMBL1452790 0.92 MAPK1 (0.39) NPC1ALDH1A1RAB9ASMN1; SMN2HTR2B
SCHEMBL5838399 0.91 PDK2 (0.31) PDK2PDK4NR1H4
SCHEMBL7053161 0.90 PDCD1 (0.34) PDCD1CD274ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590174-B2 Curable compositions comprising telechelic polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-31 US disclosed
EP-3902808-B1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3902810-B1 CURABLE COMPOSITIONS COMPRISING TELECHELIC POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
US-20250333549-A1 Process for Preparing a Catalyst for Olefin Polymerization HANWHA SOLUTIONS CORP (KR) 2025-10-30 US disclosed
EP-3356374-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP disclosed
EP-3875496-B1 METHOD FOR PREPARING CATALYST FOR OLEFIN POLYMERIZATION HANWHA SOLUTIONS CORP (KR) 2025-09-03 EP disclosed
US-12384859-B2 Process for preparing a catalyst for olefin polymerization Hanwha Solutions Corporation (KR) 2025-08-12 US disclosed
EP-3902807-B1 ORGANOMETALLIC CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-09 EP disclosed
US-12351707-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-08 US disclosed
US-12275810-B2 Telechelic polyolefins and processes for preparing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-15 US disclosed
US-5770753-A ADDITION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-06-23 US disclosed
EP-0692505-B1 Process for procucing propylene block copolymers MITSUBISHI CHEM CORP (JP) 1998-01-28 EP disclosed
EP-0576970-B1 Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts HOECHST AG (DE) 1998-01-14 EP disclosed
EP-0790076-A2 Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-20 EP disclosed
EP-0776913-A2 High molecular weight copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-04 EP disclosed
US-5623022-A VAPOR PHASE; USING COORDINATION CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1997-04-22 US disclosed
EP-0692505-A2 Process for procucing propylene block copolymers MITSUBISHI CHEMICAL CORPORATION (JP) 1996-01-17 EP disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed
EP-0576970-A1 Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590174-B2 Curable compositions comprising telechelic polyolefins CCT2, TCP1, ECH1 PDCD1 1990/4885CD274 961/4885ADRA2A 2776/4885
US-12351707-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PDCD1 1205/4885CD274 1050/4885ADRA2A 4764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.